10 Symptomatic intracranial hemorrhage occurred in 6.2% of patients receiving alteplase. Advanced imaging was used for patient selection.
#Icad stroke Activator#
Intravenous tissue plasminogen activator (alteplase) use up to 9 hours after symptom onset (the current standard is up to 3–4.5 hours after symptom onset) was tested in a randomized setting and was found to be beneficial, with modified Rankin Scale (mRS) scores of 0 to 1 reported in 35% of alteplase users and 29% of the placebo group. 9 This will give practitioners alternative strategies that can be leveraged against difficult clots.
COMPASS is a multicenter, randomized, noninferiority study that found that contact aspiration was a safe and efficacious alternative to stent retriever thrombectomy in a pool of 270 patients with large vessel occlusion (LVO). 8 This year, there was a deep dive into techniques of thrombectomy by testing stent retrieval versus contact aspiration. 6,7 As a field, it was recognized that the time window is no longer critical to successful patient outcomes but rather the individual patient tissue window, a unique characteristic born out of collateral supply. This year in endovascular therapy for stroke, the field continued the momentum from the 2018 successes of the DAWN and DEFUSE 3 studies. INNOVATION CONTINUES IN ENDOVASCULAR STROKE THERAPY
#Icad stroke free#
Speaking on passion, Kipchoge noted, “…only the disciplined ones in life are free if you are undisciplined, you are a slave to your moods and passions”-a point that registers not only within athletics but also within many occupations, including academic medicine. It took 41 elite pace runners, shoe technologic advancements, and one failed attempt last year to bring about this feat. 5 On his achievement, Kipchoge stated, “I can tell people that no human is limited.” The story of the sub–2-hour attempt best exemplifies how people, technology, and passion drive unthinkable outcomes. On October 12, 2019, Eliud Kipchoge advanced predictions for mankind by more than a decade by running the first sub–2-hour marathon (1 hours, 59 minutes, 40 seconds), a mark that modern statistical extrapolations gave a 10% chance of occurring in 2032. The progress of the last year serves as a reminder of the triumph of human spirit over adversity. The past year has seen its fair share of achievement both within medicine and beyond.
This past decade saw both the rise (2010), the fall (2013–2014 with IMS-III, 1 SYNTHESIS Expansion, 2 and MR RESCUE 3), and the resurgence (2015–present, starting with MR CLEAN 4) of likely one of the greatest modern therapies medicine has to offer-mechanical thrombectomy. For decades, the year 2020 has been portrayed as the pinnacle of human advancement and achievement, the age of artificial intelligence (AI), and more. The year 2019 has come to an end the end of a decade and the beginning of one of the most fabled of futuristic years in cinema.